产品货号:
JN1213
中文名称:
重组人淋巴细胞胞浆蛋白2(LCP2)
英文名称:
Recombinant Human Lymphocyte cytosolic protein 2/SH2 Domain-containing Leukocyte Protein of 76 kDa
产品规格:
10μg|50μg|500μg|1mg
发货周期:
1~3天
产品价格:
询价
本品由我们的大肠杆菌表达系统制备而成,目的基因编码的Met1-Pro533在N端含T7标签,C端含有His标签。
LCP2质量控制:>95%(还原性SDS-PAGE)
LCP2制剂:液体
LCP2保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。
关于LCP2:
Lymphocyte cytosolic protein 2(LCP2)contains a SAM domain and a SH2 domain. It is highly expressed in spleen, thymus and peripheral blood leukocytes, T-cell and monocytic cell lines, but expressed at lower level in B-cell lines. LCP2 was originally identified as a substrate of the ZAP-70 protein tyrosine kinase following T cell receptor (TCR) ligation in the leukemic T cell line Jurkat. It is phosphorylated after T-cell receptor activation by ZAP70, ITK and TXK, which leads to the up-regulation of Th1 preferred cytokine IL-2 during post-translational modification. Studies using LCP2-deficient T cell lines or mice have provided strong evidence that SLP-76 plays a positive role in promoting T cell development and activation as well as mast cell and platelet function.
相关搜索:重组人淋巴细胞胞浆蛋白2(LCP2)
LCP2质量控制:>95%(还原性SDS-PAGE)
LCP2制剂:液体
LCP2保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。
关于LCP2:
Lymphocyte cytosolic protein 2(LCP2)contains a SAM domain and a SH2 domain. It is highly expressed in spleen, thymus and peripheral blood leukocytes, T-cell and monocytic cell lines, but expressed at lower level in B-cell lines. LCP2 was originally identified as a substrate of the ZAP-70 protein tyrosine kinase following T cell receptor (TCR) ligation in the leukemic T cell line Jurkat. It is phosphorylated after T-cell receptor activation by ZAP70, ITK and TXK, which leads to the up-regulation of Th1 preferred cytokine IL-2 during post-translational modification. Studies using LCP2-deficient T cell lines or mice have provided strong evidence that SLP-76 plays a positive role in promoting T cell development and activation as well as mast cell and platelet function.
相关搜索:重组人淋巴细胞胞浆蛋白2(LCP2)